When your eyes are dry, burning, or irritated because of Dry Eye, Refresh Optive offers relief with not just one, but two active ingredients. Providing long-lasting hydration, this specially designed formula moisturizes and protects the cells of the eye that can become damaged due to Dry Eye. Safe to use with contact lenses. Long-lasting hydration for dry, burning, irritated eyes Lubricating and hydrating formula penetrate the eye's surface to relieve dryness Safe to use with contact lenses Convenient multi-dose bottle Safe to use as often as needed Inventiv Health Research & Insights Treatment Answers.